Clinical Trial Drugs


Individuals are encouraged to participate in clinical trials that will further the understanding of our conditions and their diagnosis, treatment, and cures. Please go to clinical trials and search on key words “primary lateral sclerosis” or “hereditary spastic paraplegia” to find out about relevant clinical trials.

Some studies for related motor neuron diseases and other neurodegenerative conditions involving over the counter vitamins, food supplements and FDA approved drugs are showing encouraging results. Some individuals with HSP or PLS, with the advice of their physician, are taking these compounds as part of their treatment plans.

The list below is provided as an informational source and is not intended to be a recommendation. For detailed information, contraindications and side effects, please visit Medline Plus Health Information. For information on vitamins and food supplements, visit the USDA Food and Nutrition Information Center. And of course, consult your doctor or pharmacist.

FDA approved treatment for ALS
Drugs and supplements with compelling data

Return to List >>