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SPF Vision: The day where all individuals with HSP or PLS are diagnosed, treated and cured.

State of HSP Research:The Promise and the Reality

by Allen Bernard

First the good news. Researchers working on hereditary spastic paraplegia, better known as HSP, know more today than ever before. They are uncovering new linkages between the proteins that are at the heart of the disorder all the time. This is good because the more common themes you can discover in a disease as complex and mysterious as HSP, the better. These themes, or nodes as they are also called, help cell biologists map the disease and understand why so many different variants — SPG3A, SPG4, SPG31, etc. — cause the same common problem: lower limb spasticity and high muscle tone.
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News And Events

Meditation as Medicine

Scientific evidence from well-designed research studies shows that meditation can increase attention span, sharpen focus, improve memory, and dull the perception of pain. What… say that again… meditation can help with pain! In the spring of 2000, Cassandra Metzger was working as an attorney at the Public Broadcasting Service headquarters in Washington, D.C., attending night [...]

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SPF-Illinois Connection

We met at Hank’s condominium clubhouse.  For lunch we ordered Jimmy Johns’ subs and had the driver take the connection picture. We had 12 in attendance at this our third meeting. We discussed medications, the Baclofen Pump, what the Baclofen pump looks like installed, what the procedure is before a pump is installed. We also [...]

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Country Music Marathon

I completed the very wet Country Music Half Marathon yesterday. Achilles guides by my side. I finished 3rd in my division. Braden finished up the Kids Marathon today. We are hoping he will be a Cross Country athlete. The Achilles athletes made the local paper. We started just before the main race. Can you pick [...]

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Aussies Seeking a Treatment for SPG4/spastin

It was a satisfying achievement to finally publish the results of the last 3 years work that was supported by funding from the Australian HSP Research Foundation. Our study concentrated on understanding how cells from HSPers and non-HSPers differed in order to learn how the genetic mutations in the spastin gene lead to the disease.  [...]

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