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Welcome to Spastic Paraplegia Foundation, Inc.

HSP and PLS are neurological disorders affecting the voluntary muscles. The disorders are progressive and may lead to patients being unable to walk, and more. The Spastic Paraplegia Foundation is dedicated to advancing research and finding cures for two groups of closely related, progressive neurological disorders: Primary Lateral Sclerosis (PLS) and Hereditary Spastic Paraplegia (HSP).

SPF Vision

The day when all individuals with HSP or PLS are diagnosed, treated, and cured.

News & Announcements

Our Impact since our inception...

  • Dollars Raised

    Over 11,000,000 dollars for research!

  • Linda Lafontaine
    Linda Lafontaine

    I've been dealing with HSP for a very long time. Then I joined a support group and I found the Spastic Paraplegia Foundation. Hopefully I can spread awareness and get others to join the Foundation.

Thank you to our generous sponsors.

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