Each day, the Spastic Paraplegia Foundation is working to change the future for those living with Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS), rare neurodegenerative diseases that currently have no cure. Through research funding, advocacy, and community support, SPF is giving thousands of families something that once felt out of reach: HOPE. This Giving Tuesday, December 2, 2025, your generosity goes even further. Every donation will be matched dollar-for-dollar through our End-of-Year Match Campaign, doubling your impact and helping us reach our goal to fund even more groundbreaking research in 2026. Every donation made through December 31, 2025, counts toward our $300,000 End-of-Year Match Goal. If you already donated this year, thank you! If you can, any amount will be matched dollar-for-dollar.
Our Impact since our inception...
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Dollars Raised
Over 12,000,000 dollars for research!
