HSP

The short answer appears to be “yes”, although it is important to remember that sexual desire and/or function can be affected by many other factors such as age, stress, depression, fatigue, medical disorders or medications. Some people report that stiffness, spasms and cramps that are part of HSP may either inhibit (or intensify) orgasm, or that orgasm may bring on leg stiffness, spasms or clonus. Stiffness of the legs or arms may cause difficulty using certain positions for intercourse. Baclofen, particularly intrathecal baclofen, has been linked to anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation) after a number of years of use.