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The SPF Community Comes Together for the 23rd HSP/PLS Annual Conference in St. Louis, June 15-17th!  LEARN MORE

PLS

About PLS (Primary Lateral Sclerosis)

General Information

This material has been reviewed by Dr John Fink, M.D., SPF Medical Advisor. Please see the Glossary to help with medical terms.

The disorder usually begins in the legs but can begin in the upper body or bulbar (speech and swallowing) muscles. The age of onset is generally between 35 and 66 years of age.

Is PLS more prevalent in certain ethnic groups?

A Work in Progress

Neurologist & Psychiatrist

Dr. Deborah Warden

Deborah developed a mysterious neurologic illness, later to be revealed as PLS, while working with military blast TBI patients.

Visit her website to find out more about her. 

Listen to her speak in a July 2025 speech using a voice clone recently made by Eleven Labs. You can compare the voice clone to the beginning of the video to see how similar the voice clone is to her original voice HERE

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