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The SPF Community Comes Together for the 23rd HSP/PLS Annual Conference in St. Louis, June 15-17th!  LEARN MORE

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2026 HSP/PLS Annual Conference

Monday, June 15, 2026Wednesday, June 17, 2026

The Spastic Paraplegia Foundation (SPF) is thrilled to invite you and your family to join us in St. Louis, Missouri, June 15–17, 2026, for our 23rd SPF HSP/PLS Annual Conference—a meaningful, welcoming gathering for patients, families, caregivers, and kids living with Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS).

Pathway to the Gateway: Roadmap to Health, Therapies & Wellness is the 2026 theme and reflects where our community is today: informed, connected, hopeful, and moving forward together. Our goal for the 2026 Conference is to thoughtfully integrate science, innovation, and lived experience—highlighting tools that can meaningfully support daily function, independence, and quality of life.

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